TITLE:
Topics in Cancer Genomics
ABSTRACT:
My talk will cover material from the following papers:
Using sigLASSO to optimize cancer mutation signatures jointly with
sampling likelihood.
S Li, FW Crawford, MB Gerstein (2020). Nat Commun 11: 3575.
Latent Evolutionary Signatures: A General Framework for Analyzing
Music and Cultural Evolution
J Warrell, L Salichos, M Gancz, MB Gerstein (2024). J R Soc Interface
21: 20230647.
Assessing and mitigating privacy risks of sparse, noisy genotypes by
local alignment to haplotype databases.
PS Emani, MN Geradi, G Gursoy, MR Grasty, A Miranker, MB Gerstein
(2023). Genome Res 33: 2156-2173.
Unified views on variant impact across many diseases
S Kumar, M Gerstein (2023). Trends Genet 39: 442-450.
Passenger Mutations in More Than 2,500 Cancer Genomes: Overall
Molecular Functional Impact and Consequences.
S Kumar, J Warrell, S Li, PD McGillivray, W Meyerson, L Salichos, A
Harmanci, A Martinez-Fundichely, CWY Chan, MM Nielsen, L Lochovsky, Y
Zhang, X Li, S Lou, JS Pedersen, C Herrmann, G Getz, E Khurana, MB
Gerstein (2020). Cell 180: 915-927e16.
Origins and characterization of variants shared between databases of
somatic and germline human mutations.
W Meyerson, J Leisman, FCP Navarro, M Gerstein (2020). BMC
Bioinformatics 21: 227.
i0md24
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