Saturday, September 30, 2017

Re: Title for HGVS talk

Abstract for
HGVS presentation - 17th October, Orlando, Fl

My talk will focus on prioritizing genetic variants associated with
cancer, to identify key variants driving cancer progression. First, I
will look at the overall functional impact of the variants in cancer
genomes, ranking them in terms of impact, for both coding and
non-coding regions. For the coding analysis, we use the ALoFT and
frustration tools, and for the noncoding analysis, we use FunSeq.
Then, I will look at the recurrence of variants within cancer cohorts.
Here we develop two approaches: one parametric (LARVA) and the other
non-parametric (MOAT). Finally, I will put these methods together
through application to kidney and prostate cancers.

http://events.hgvs.org/
9:00 - 9:40
10/17

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1 comment:

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