the abstract for my talk, "AI Approaches for Understanding Brain Disorders":
My talk will concern the use of endophenotypes to make more useful and
precise genetic associations. First, I will look at using large-scale
brain single-cell data to better connect genotype to neuropsychiatric
phenotypes and then to use these connections in a deep learning model
to simulate perturbations related to brain disease. Next, I will
examine an endophenotype derived from wearable biosensors, such as
smartwatches, and demonstrate that this digital phenotype can uncover
more genetic associations for brain disease than traditional clinical
associations.
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eur25+ebi
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